Home away from home doesn't necessarily have to mean staying at familiar chain hotels. If you're looking for a unique experience that starts with where you'll sleep each night, you'll find plenty of charming and luxurious hotels and bed and breakfasts throughout Pittsburgh. Get away from the hustle and bustle of everyday life without trekking too far from home. Or, invite loved ones to visit and book them a room at one of these unique places to stay in Pittsburgh PA - all of which are unforgettable.

Stay in luxury at the Priory Hotel, billed "Pittsburgh's only historic boutique hotel," on the North Side. The 40-room boutique hotel promises tranquility within walking distance of the city. The long list of amenities includes an on-call shuttle to zip you from one spot to another, a fitness center, a business center, and a common room with a wood fireplace. Raise a toast to the luxury of the Priory at Monks Bar on-site, known as the smallest bar in the state with only 14 seats. Book your stay on the official Priory Hotel website.

Walk through the black iron gates, surrounded by bright yellow and red flowers, before ascending the staircase leading to the Inn on Mexican War Streets, a charming bed and breakfast in the vibrant Mexican War Streets neighborhood. Each of the eight rooms, which includes an executive suite and a mini-suite, promises a plethora of amenities such as a daily continental breakfast, delicious chocolate chip cookies and snacks each afternoon and evening, and access to the common rooms. Learn more on the Inn on Mexican War Streets website.

Find tranquility just outside of Pittsburgh in Greensburg at the Robertshaw Country House, on the grounds of Saint Emma Monastery. The bed and breakfast, housed in a Colonial home, features four guest rooms complete with room fixtures from 1931. When not lounging in your room or around town, relax in the pine-wall library, in the living room with a piano and a fireplace, or in the elegant dining room. Reserve your stay on the Robertshaw Country House website.

Stay in the heart of Shadyside at the Inn on Negley, a charming guesthouse with eight beautifully decorated guest rooms. Start each day with the complimentary breakfast, prepared fresh by the Inn's professional chef, and enjoy the long list of amenities, including robes and slippers, a BOSE radio in the room, wireless internet, and the complimentary beverage bar. Find out why the Inn on Negley is the perfect weekend getaway in Pittsburgh by reading our previous article.

Which of these places to stay in Pittsburgh, PA are unforgettable enough that you like to visit? Let us know in the comments! For one of the most unique places to stay in Pittsburgh, check into a former convent on the South Side. Need more inspiration? Check out the available spots on Hotels.com.